The Substance

If you follow the instructions, what could go wrong?

The Substance

Released · Drama, Horror, Science Fiction

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

  • Demi Moore

    Demi Moore Elisabeth

  • Margaret Qualley

    Margaret Qualley Sue

  • Dennis Quaid

    Dennis Quaid Harvey

  • Edward Hamilton-Clark

    Edward Hamilton-Clark Fred

  • Gore Abrams

    Gore Abrams Oliver

  • Oscar Lesage

    Oscar Lesage Troy

  • Christian Erickson

    Christian Erickson Man at Diner

  • Robin Greer

    Robin Greer Male Nurse

  • Tom Morton

    Tom Morton Doctor

  • Hugo Diego Garcia

    Hugo Diego Garcia Diego - Boyfriend

  • Daniel Knight

    Daniel Knight Casting Director

  • Jonathon Carley

    Jonathon Carley Assistant Casting Director

  • Jiselle Henderkott

    Jiselle Henderkott Girl Auditioning / New Year's Eve Show Dancer

  • Akil Wingate

    Akil Wingate TV Host

  • Vincent Colombe

    Vincent Colombe Man in Suit #1 - Harvey's Office

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Direction
  • Coralie FargeatCoralie Fargeat Director
Writing
  • Coralie FargeatCoralie Fargeat Writer
Wide release
September 7, 2024 (2 months ago)
Origin
France, United Kingdom
Runtime
2h 21m
Max position
1 · October 12, 2024 (1 month and 9 days ago)
Appearances
71 days in the Top 50