During the Warring States period, the young thief Dororo encounters Hyakkimaru, a strange, sightless boy who wields fearsome prosthetics in place of his missing limbs. Parts of Hyakkimaru’s body were traded to a group of 12 demons by his father in exchange for power, but thanks to a kindly medicine man, Hyakkimaru survived his horrifying ordeal. Now he roams the land in search of his missing body, and together he and Dororo will fight to survive in an unforgiving, demon-plagued world.
Hyakkimaru has regained his voice from the devil god, but one leg was stolen from him. After returning to the deserted temple and having his wounds taken care of, he again goes into battle with the demon. Meanwhile, in the abandoned temple where Mio and the children are waiting.
Sabame has been feeding people to the demons to protect the village over which he rules. As Hyakkimaru once again confronts the demon moths, Dororo gets trapped in a storehouse.